Rosai Dorfman Disease (cutaneous) and Anterior Gr. uveitis

[Mike Bartolatz]

Juan G. Gaviria1 , Daniel A. Johnson1, Marsha C. Kinney1, Liana H. Proffer1, Jacqueline M. Losi-Sasaki1 and Eric W. Kraus1

(1) Department of Ophthalmology, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229-3900, USA

Received: 5 May 2004 Revised: 25 June 2004 Accepted: 30 June 2004 Published online: 30 September 2004

Abstract
Background Rosai-Dorfman disease (RDD) is a benign, rare, histiocytic disorder of unknown etiology. We describe the case of a 61-year-old woman who presented to the ophthalmology clinic with bilateral granulomatous anterior uveitis.
Methods The uveitis was controlled on topical prednisolone acetate 1%. One month after presentation, she developed generalized macules and papules, and dermatologic and systemic evaluations were performed.
Results On the basis of skin biopsy, purely cutaneous RDD was established.
Conclusion Anterior granulomatous uveitis may be the presenting sign of cutaneous RDD. Consultation is necessary for accurate diagnosis.

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Juan G. Gaviria
Email: juangaviria@lycos.com


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