Humira + Uveitis

[m_rajatish]

I am a remote patient of Dr. Foster's (see him once every 6 months) and was recently put on Humira in addition to Methotrexate to stop the latest bout of Iritis. Have had roughly 5 bouts over last 12 years. I am HLAB27+ve - sleight of fate I suppose.

Based on the extensive learnings from people in this forum, I wanted to get a sense how long it takes before Humira shows effect or before we realize it will not show effect? I started 2 weeks back (May 9th), so back to back 40 mg on May 9th and May 16th and next doses will be 2 weeks out from now. Methotrexate will continue weekly. So far, I don't know if I am seeing any changes but in talking to my local doctor, he said at least 4-6 weeks before even the first effects show.

All thoughts and experience sharing appreciated. And my hope is everyone finds a way to calm this nasty recurring disease in their own way without steroids.
Thanks,
/Raj

[vancouver]

https://www.tapatalk.com/groups/uveitissupport/



Hoping reproxalap works.

[kwork]

It can take several months before you will see full effect so don’t give up.

[m_rajatish]

An update to all on progress and lack there-off and as always, your thoughts and wishes count more than anything else:

1. Vision: Vision progressively improved with steroids. Down from every hour to 8 times to 4 times to 2 times. But then at 2 times, some cells re-appeared. Local Uveitis specialist feels we should have gone from 4 down to 3... hindsight is 20/20, lets hope that doesn't destroy my eyesight

2. IOP: I am a steroid responder. On several drops and on pills, yet pressure up to 26 now. Will probably go up even more esp. since drops are now increased to 4 times. It will all depend on how soon the horrible inflammation settles down.

3. Other body pain (esp. upper back): I seem to be noticing significantly less body pain but could be temporary - not sure. Is this first signs of Humira working or am I just being hopeful when I shouldn't be?

It seems the battle is between inflammation and pressure for now. My doctor added Rhopressa, a new IOP reducing drop - will start it tomorrow. If nothing works, might need to go for surgery.

I hope there is an end to this nightmare and there is a morning that is bright with some sunlight I can see.

[vancouver]

Dr fosters site is better or oliviasvision. Some doctors and studies say that there is nothing unique about hlab27 iritis. You are just as likely to have difficult Iritis
If you are idiopathic. I was never tested at all and have difficult Iritis.

[m_rajatish]

I am HLAB 27 +ve and its chronic uveitis. I am very much hoping the inflammation calms down with increased steroid drops.

[vancouver]

I am HLAB 27 +ve and its chronic uveitis. I am very much hoping the inflammation calms down with increased steroid drops.

I'm praying for you,my friend.

[m_rajatish]

Thank you - I hope to survive this and contributing to the community to help others.