My predicament

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sgbakegirl80
Posts: 3
Joined: Sun May 27, 2012 8:52 pm

My predicament

Post by sgbakegirl80 »

Episode 1 (2010)

First attack of iritis on right eye. Officially diagnosed with severe acute irido cyclitis. Was tested for TB, FTA-ABS and HLA B27. Found to be HLA-B27 positive. Doctor notes says 3+ inj, 1+ flare, small kp, 0.2mm hypopyon, synechiae, dense fibrin on a.c...etc

Treatment:
5% homatropine
pred forte 1% every hour
60mg prednisone daily

The experience:
Stabbing eye pain. blood shot eyes, senstivity to light, watery eyes, vision was terrible. However, with aggresive treatment, gradually inflammation subsided and vision returned to normal.

Episode 2 (2012)


Second attack kinda creeped in quietly. At the end of April some redness started to creep in at corner of left eye. Waited a few days and in less than a week it had turned a bright red and there was sensitivity to light. Saw my PCP, told her about my iritis hisory was refered to in-network Opthamologist and was diagnosed with viral conjunctivitis. Medication did not work. Vision deteriorated. In less than a week back at Opthamologist refered to UIC uveitis specialist prescribed generic steroid drops (4 times a day & Bromday once a day). Uveitis specialist cannot accomadate me till 3 weeks later and even then is a maybe. UIC general eye clinic agreed to look at me. This is where i had received my treatment during my first attack. Was told that i had inflammation at the back of the eye (heard something about borderline 3+, non granulomatous) and possible cyst in infected eye. They used a contraption to take pictures of my eye though strangely it seemed more comprehensive on my right eye than my left eye. But whatever. Was told it looked normal.

Treatment:
Pred Forte (6 times daily)
5% homatropin (once before bed time)

The experience:
Very different experience. Mostly painless. Apart from 1-2 days of pain in the back of the eye. Pain resided somehow. However, vision is much worse this time round. Eye was remaining fully dilated for 5-6 days. Even after i personally decided to halt the dilating drops till my pupl came close to normal size vision would be close to what it was in the morning when i wake up @ 20/30 or 20/40 and as the day progressed it gets blurrier and by the end of the day it usually goes dow all the way to 20/100 or 20/200. Apart from looking a little glazed over, eye superficially looks pretty normal with no obvious inflammation.

MY PREDICAMENT
I have an HMO and everything depends on getting a referal. My follow up appointment is 2 weeks from my first and it is this Friday. I am concerned about my overly dilated pupil that is staying dilated longer than the last time. I am also concerned about my severly reduced vision with gets worse as the day goes on. I don't know if it is typical for two attacks to react so differently. Are there specific questions i should be asking my doctor? Should i be pushing the doctor to do blood tests to see if anything systemic or an autoimmune disease is taking its course. Apart from unusually dry skin, stuffy ears, 30-35lbs of weight gain since 2010, low libido, irratibility and sluggishness i have no other symptoms.

Sorry for this super duper lengthy post. Just feeling a little helpless and just not sure if i am being treated effectively this time round. Not allowed to go back to work till my vision improves :(

If you read this far i wanna say thank you. Please reply if you have the same issues or you would like to share your thoughts on this insanity.

Thank you.
Mike Bartolatz
Posts: 6595
Joined: Fri Feb 06, 2004 9:58 pm

Re: My predicament

Post by Mike Bartolatz »

get in to see the uveitis specialist at UIC, Dr Goldstein. she may give you a corticosteroid injection to tissue surrounding your eye or oral steroids to calm this down. with HLA B27 uveitis, often adding an NSAID such as celebrex, Dolobid or Naprosyn taken at Prescription strength will help calm this down. if not, then you will require a corticosteroid sparing approach to treatment using DMARD drugs or other classes of medications such as Remicade or humira to put you into remission.

you need the dilating drop as it relaxes the ciliary body and minimizes adhesion from the synecia, pus that causes the adhesion between the iris and the lens. it can take several days for the dilating drop to get out of your system and for the iris to close completely but while you have so much inflammation, STAY ON THE DILATING DROP.
yes some testing would be appropriate beyond geh HLA B27 test such as flims of your lower lumbar region to look for ankylosing spondylitis, reactive arthritis, Crohn's disease etc all linked to this gene. treating the inflammation related to these conditions is critical in stopping the recurrent nature of HLA B27 uveitis.

with inflammation in the middle or back of the eye, steroid eyedrops will NOT help as they cannot penetrate that deeply into the eye. you also have iritis so continuing them is appropriate. to stop the inflammation in the rest of the eye, you will need either steroid injections to tissue surrounding your eye or for Oral corticosteroids.

hormone levels should also be tested such as thyroid, diabetes and even testosterone as this can also impact stuff in women.
get your vitamin D3 levels checked too as well as vitamin B12 and calcium levels.
SED rate and C reactive protein to look for systemic inflammation should also be tested for,

wishing you quiet eyes,
mike
autoimmune thyroid disease is often found along with the above conditions and is linked through additional genes, IL23R, ERAP1.
Mike Bartolatz
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sgbakegirl80
Posts: 3
Joined: Sun May 27, 2012 8:52 pm

Re: My predicament

Post by sgbakegirl80 »

thank you! thank you!

your informative reply is going to be invaluable. will definitely mention some of the suggestions you have listed to my doctor. might even go in with a checklist of my symptoms.

was told by my current dr at the general eye clinic that dr goldstein is moving or leaving.... not sure how true this is but will double check with him if an appt with dr goldstein is going to be possible.

hopefully will make more progress at tomorrow's appt.

thank you!
Mike Bartolatz
Posts: 6595
Joined: Fri Feb 06, 2004 9:58 pm

Re: My predicament

Post by Mike Bartolatz »

the other specialists in Chicago are DR Howard Tessler (was at UIC but retired but is still practicing) and DR Anthony Ekong who trained under Dr Foster at Harvard.
contact information for them can be found at http://www.uveitis.org in the PATIENT informaton section of the site on the SPECIALIST list (HOTLINK)

wish you the best,
Mike
Mike Bartolatz
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